There are a large number of rejuvenation methods. One of the popular procedures is biorevitalization using SKIN preparations, developed by the Italian laboratory ItalFarmacia. Let's take a closer look at one of the four products in the line - the biorevitalizant Skin-R, which strengthens and models the dermal matrix, created to act in hypotonic areas of the face and body, primarily the neck and décolleté, as well as the arms and hands, and abdomen. The solution has the most gentle effect on the skin, while starting renewal processes and allowing you to quickly achieve a visible effect. This method of anti-aging care is safe and has few contraindications. Reviews from doctors and patients confirm the positive effect of the drug on the condition of the skin and appearance.
Product Description
Biorevitalization SKIN (Skin) is an injection procedure using drugs from the Italian company Italfarmacia.
The know-how of SKIN products is the use of short fragments of low molecular weight hyaluronic acid, consisting of 20-38 monomers.
A number of studies indicate that it is precisely such small chains that more easily bind to specific CD44 receptors on fibroblasts, activating their production of the most important substances for the skin - collagen and elastin.
In addition, the composition includes amino acids necessary for the synthesis of dermal protein structures.
The manufacturer claims that thanks to this approach, the procedure promotes not only deep hydration, but also a kind of biostimulation of the skin - activation of its biological functions by stimulating cells to divide and form their own collagen.
Compound
Biorevitalizants of the SKIN line are based on the action of the following components:
- hyaluronic acid of biosynthetic origin in the form of oligosaccharide fragments is designed to improve the elastic characteristics of the skin;
- amino acids restore the skin, strengthen its immune defense, and exhibit antioxidant properties;
- The carbonate buffer maintains physiological pH values as close as possible to the natural values of the dermis.
Manufacturer
Italfarmacia Ltd. is a company founded in 1995 in Italy, specializing in the production and sale of medical devices, nutritional supplements and cosmetics.
SKIN products were first introduced in 2005. Maurizio Cicarelli, a professor of medicine, director of the International Center for Study and Research in Aesthetic Medicine, who is called a genius in the field of aesthetics, took an active part in its creation.
It was the developments of Maurizio Cicarelli that formed the basis of the drugs.
Reviews
Marina, 46 years old: “Over the last ten years I have started to age dramatically. I haven’t decided to go for plastic surgery yet, but I want to look young. On the advice of my daughter, I decided to undergo Skin biorevitalization. There were injections into the face and décolleté area. The redness went away within an hour. The first week the result was not particularly visible, I even wanted to stop the course. But my daughter persuaded me to go to the end. After two months, the result is obvious - the cheeks are tightened, and the décolleté area is not so flabby. There is still an effect from the procedure!”
Natalya, 30 years old: “I read positive reviews about Skin products on social networks. I decided to take the course before my anniversary. The cosmetologist said that Skin B would suit me, although I thought it was for very young people. After six procedures, the face became so velvety, and the wrinkles above the upper lip disappeared.”
Vika, 33 years old: “After pregnancy I managed to get my figure back, even my stomach became flat. The only thing that upset me was the skin on my stomach, wrinkled and stretched. Massage and exercise didn't help much. And Skin R biorevitalization worked! Now my stomach is elastic and hard!”
Review of biorevitalizants
SKIN-B
Starter preparation for skin biostimulation.
Recommended for correcting early age-related skin changes and preventing their subsequent development. It perfectly moisturizes the skin and evens out the tone, eliminating minor imperfections. Due to its light formula, it is ideal for young skin.
SKIN B is also often used for preparation before injections of other biorevitalizants in this line.
Indications:
- the first signs of aging;
- dry, dehydrated skin;
- small superficial wrinkles;
- dull uneven tone;
- dark circles under the eyes.
SKIN-Colin
Colin product is designed for instant lifting and biostimulation of the skin.
In addition to hyaluronic acid and an amino acid complex, it contains an additional component - choline bitartrate.
It has the ability to stimulate myofibroblasts - cells that are both similar to fibroblasts (skin cells) and smooth muscle cells. By expanding blood vessels, choline improves microcirculation and nutrition of the dermis, and activates gas exchange.
In addition to traditional intradermal injections, SKIN-Colin can also be injected specifically into the facial muscles. Such toning allows you to increase muscle tone, improve the oval and contours of the face, and tighten the upper eyelid.
Indications:
- initial and moderate manifestations of age-related skin changes;
- decreased tone and elasticity;
- skin dehydration;
- laxity and sagging.
SKIN-OX
The drug SKIN-OX combines the effect of biostimulation and antioxidant action.
The active ingredient is sodium ascorbyl phosphate, a stable form of vitamin C.
By blocking tyrosinase, an enzyme that provokes the formation of age spots, it effectively lightens the skin, eliminating existing manifestations of hyperpigmentation and preventing subsequent photodamage.
Glutathione and cysteine in the composition prolong the effect of vitamin C and enhance protection against the damaging effects of free radicals.
The product can be used as monotherapy or in combination with other drugs in the line - Skin-B and Skin-Colin.
Indications:
- skin hydration;
- pigmentation disorders;
- prevention and treatment of rosacea;
- "smoker's skin"
- aggressive influence of the sun.
SKIN-R
A powerful drug for starting the process of restructuring and biotransformation of the dermis.
The product has a maximum content of hyaluronic acid, which allows you to achieve a pronounced rejuvenating effect.
The key difference from other products in the series is the use of a hypertonic solution with an altered, acidic pH. This allows for additional trauma to the dermis and the launch of response skin repair processes.
The result is the formation of “fibrotic”, rapidly synthesized type I collagen, skin tissue tension and an instant lifting effect.
It should be noted that due to its osmotic properties, SKIN-R injections may be accompanied by high pain.
Indications:
- pronounced age-related skin changes;
- superficial and deep wrinkles;
- decreased tone and elasticity;
- loose body skin.
Indications and contraindications for skin biostimulation Skin B
- For the youngest skin, starting from 25 years:
– as monotherapy, prevention of fading, moisturizing, before tanning, recovery from stress, illness.
- For more mature skin:
– as a necessary initiation, active starting therapy before more serious procedures of contouring, botulinum therapy, laser resurfacing, deep or medium peels, which will provide the skin, support it and nourish it with all the necessary micro- and macroelements.
- For skin aged 45-50 years:
– to activate all rejuvenation processes in the body.
The procedure is contraindicated in case of individual intolerance to the components of the drug.
Cost of the drug and where you can buy it
SKIN biorevitalizants are produced in group packaging - 3 ampoules of 5 ml.
They can be ordered on specialized online platforms. To make a purchase, you must confirm your professional status by presenting a medical education diploma.
For specialists, the right decision would be to purchase the product from the official distributor in Russia, which also conducts educational seminars.
The price is about 3,500 rubles. When purchasing, be sure to check for quality certificates.
The best solution for patients is to contact their cosmetologist or a clinic where this procedure is performed.
How is Skin L used?
This solution, used for biorevitalization together with the drug "Skin B", is characterized by almost identical properties with it. The above products differ in the technique of manipulation and the depth of insertion into the skin.
All other agents are often administered papually, namely at a shallow depth, and after the injections small “hailstones” appear on the skin, dissolving during the first day after the procedure.
Skin L is injected deeper and does not cause such an external effect. But its internal impact is much stronger. However, you cannot use the solution at your own request; this requires indications that must be taken into account by a specialist.
Most reviews of biorevitalization with products from the Skin series (Skin L) are positive, as with all products in this line.
“I have been using Skin preparations for the biorevitalization procedure for a long time. I always like the effect, that’s why I didn’t look for alternative means. But one day my cosmetologist advised me to try Skin L, explaining this recommendation by a longer-lasting result, as well as the absence of papules, which took quite a long time to resolve (about two weeks). I followed the advice and have never regretted it. The result was brighter, the swelling after the injections was insignificant, and there were no “pimples” at all. Of course, I liked everything!”
(Nina, 47 years old)
Carrying out the procedure
How it goes
The procedure takes about 1 hour. First, make-up is removed and the skin is thoroughly cleansed.
For greater patient comfort, anesthetic cream is applied to the areas undergoing the procedure for 30-40 minutes. After this, the skin is disinfected with an antiseptic solution, and the doctor proceeds directly to the injections.
Biorevitalization is mainly carried out using the papular technique: small doses are administered intradermally at a distance of about 1 cm from each other. At the same time, so-called papules are formed at the injection site, which disappear as it resolves.
SKIN-B, due to its light consistency, allows the use of an even less traumatic method of administration - injections are made only at certain points, and the drug spreads to surrounding tissues due to diffusion.
Features at different ages
The line includes products created taking into account the needs of skin at different ages.
- SKIN-B is the optimal choice for young patients over 25 years of age. Eliminates skin dryness, flaking, dullness and uneven color.
- SKIN-Colin is an effective solution for people aged 30-35 years. Works on superficial wrinkles and sagging skin.
- Skin-OX – help in solving skin problems after 35. Effectively fights pigment spots and color unevenness.
- SKIN-R – extreme lifting for age 45. Along with this, the product can be used at any age against sagging skin on the neck, décolleté, hips, abdomen and other areas of the body.
It should be noted that such a division is conditional, and the choice of the optimal remedy should be entrusted to a doctor. He is the one who will be able to correctly assess the needs of the skin and choose the best treatment option.
As an alternative to SKIN biorevitalizants, you can also consider professional “REJU” products from the “DG-skin” series based on hyaluronic acid, trehalose and amino acid-peptide complex, the Italian drug Natinuel Skin Normalize, the Skin Wise line and others.
Course duration
The number of necessary procedures depends on the initial condition of the skin and is determined by a cosmetologist. On average, 4 to 7 sessions will be required depending on the product chosen.
- Biorevitalization of SKIN B, Colin and Ox, as a rule, involves 6 repetitions: the first 4 are performed once a week, and the next 2 - once every 2 weeks.
- The standard SKIN R course consists of 4 sessions with an interval of 14 days. To maintain results, it is recommended to repeat injections every 4 months.
In addition, experienced specialists often combine drugs based on the needs of the skin.
Operating principle
The basis of skin renewal using Skin-R technology is fragments of hyaluronic acid that can activate fibroblasts, as well as amino acids that promote the natural production of dense collagen. In the process of exposure to the natural components of the drug, structural changes in the dermis occur, aimed at increasing its hardness. This is why the Skin-R technique is called biorestructuring.
The role of hyaluronic acid
Hyaluronic acid is synthesized in the body, its production maintains skin elasticity. The older a person gets, the less it is produced. Because of this, the appearance loses its shine, wrinkles and sagging appear.
Biorevitalization products help saturate the dermis with hyaluronic acid from the outside, as well as increase its synthesis from the inside. This returns turgor, which instantly improves the condition of the face and visually removes up to 10 years of age. This effect is achieved due to the properties of the active substance of the drugs:
- moisture is retained inside the cells, straightening them and removing creases;
- the skin becomes dense in appearance and elastic when pressed;
- sagging areas are tightened due to improved structure and powerful hydration;
- the thickness of the deep layers increases.
Hyaluronic acid molecules are too large to penetrate through pores. Therefore, they are administered by injection.
This allows you to act from the inside, causing a noticeable effect immediately after use. Due to the fact that the active substance is normally present in the skin, biorevitalization preparations extremely rarely cause allergic reactions.
Healing period
It should be noted that the rejuvenating procedure is accompanied by the formation of papules at the injection site.
The speed of their resorption depends on the density of the selected drug.
Papules resolve most quickly when using Skin B. And the longest recovery period is observed after the introduction of Skin K (up to 48 hours).
Side effects
The injections themselves are quite safe. Most often, patients are concerned about the pain of their insertion, redness of the skin immediately after the procedure, and slight swelling.
If the needle injures a blood vessel, hematomas and bruises may occur.
More serious side effects require immediate medical attention.
Side effects
Biorevitalization is a minimally invasive procedure, and therefore is rarely accompanied by undesirable manifestations. But due to the injection of drugs, complications may arise:
- swelling of the treated area;
- microhematomas at injection sites;
- redness of the skin.
These signs disappear after some time. If after 48 hours the treatment area is still bothering you, you should contact a specialist. He will prescribe a wound-healing and anti-inflammatory ointment that will help relieve negative consequences.
Precautionary measures
To ensure that the procedure is easy and without unpleasant consequences, special attention should be paid to choosing a doctor.
He must have a higher medical education and specialization in cosmetology. Biorevitalization is not a particularly complex technique; however, it is better to give preference to a doctor who has experience and relevant training certificates.
In addition, special attention should be paid to pre-procedure preparation and subsequent post-injection care.
2-3 days before the procedure you must:
- give up alcohol;
- Avoid taking anticoagulants (aspirin, heparin, etc.).
After the procedure, exclude for 2-3 days:
- physical activity, sports;
- thermal procedures (bath, sauna, hammam);
- intense ultraviolet irradiation (including solarium).
be careful
To minimize the risk of possible side effects, follow specific directions. If this is necessary, the doctor will give you personal advice. If we talk about general rules, then among them it is worth listing:
- use of special antiseptic cosmetics;
- following advice on maintaining a healthy lifestyle, which increases immunity and protects against possible infections;
- refusal to go to the pool or open water;
- refusal to visit saunas, baths, steam rooms - rooms with high humidity and temperature.
Comparison with other popular fillers
Skin wise - a line of fillers and biorevitalizants is distinguished by a wide range and fast recovery. Prescribed for different age groups, for treatment and skin rejuvenation. The effect lasts up to 14 months.
Teosyal - contains hyaluron and lidocaine, which reduces pain during implantation. The non-animal origin of the acid reduces the risk of developing allergies. It has antioxidant properties, enhancing cellular immunity. Used for perioral, periorbital area, oval contouring, lip augmentation. Biodegradation occurs in 6 to 8 months.
Juviderm - there are no components of biological origin, hyaluronic acid goes through several stages of purification. Fillers of different densities are presented, which allows you to correct all types of wrinkles and use them to model oval shapes. It is distinguished by its high cost and impeccable quality, the effect lasts up to a year.
