Retinoids are effective medications for acne and wrinkles. Experts' opinion


The best creams and gels for acne.

October 22, 2022
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Content
  • Why do acne appear on the face?
  • How to choose an acne cream
  • 10 best creams and gels for acne
  • Zenerite
  • Delex-Acne
  • Baziron
  • Klenzit-S from Glenmark
  • Differin
  • Juniper from Mi&Ko
  • Clearasil Ultra
  • Lumene Nordic Girl! Clear It Up!
  • Skinoren
  • Effaclar Duo + by La Roshe-Posay

Thanks to modern acne treatments, you can quickly and permanently solve the problem. We have created a selection of the best creams and gels for those with problem skin.

Both women and men experience pimples and acne, and at any age.

conclusions

  1. You should not squeeze pimples yourself, as this can cause infection and wounds on the face.
  2. Before starting treatment, it is recommended to consult a dermatologist who can choose the right treatment.
  3. Preparations containing an antibiotic are considered effective in the fight against imperfections, since the main cause of acne is bacteria and microbes.
  4. The main active ingredients aimed at fighting acne are erythromycin, adapalene, zinc oxide, salicylic acid, benzoyl peroxide.

Why do acne appear on the face?

Among the causes of acne are such non-obvious, but very possible, as lack of vitamin D, stress, poor environment, use of sunscreen, and long conversations on the phone.

Now let's look at the common causes of acne on the face.

  1. Hormonal imbalance.
    Typically, acne appears in women during PMS, in teenage girls and in pregnant women. This is due to the fact that the level of steroid hormones in the blood increases - the sebaceous glands begin to work more intensely. Due to hypersecretion of sebum, the protective abilities of the skin are reduced. The skin secretion thickens, the ducts become clogged with plugs that block the sebaceous glands.
  2. Follicular hyperkeratosis.
    In this case, the cells with hair follicles are poorly renewed. The stratum corneum of the hair follicles becomes thicker, which prevents the outflow of secretions from the sebaceous glands.
  3. Excessive proliferation of propionic bacteria.
    There are millions of different microorganisms on the human skin and mucous membranes. But sometimes they begin to multiply uncontrollably, and inflammation is possible. Pimples appear because such bacteria feed on the sebaceous plugs of the hair follicles.
  4. Lack of zinc in the body.
    When there is a lack of zinc in the human body, the skin produces an excessive amount of sebum - hence pimples and acne.
  5. Improper skin care.
    If you use skincare products that are not suitable for your skin type or use low-quality decorative cosmetics, it is quite possible that you will develop acne.
  6. Poor nutrition and gastrointestinal problems.
    The appearance of the skin often depends on the health of the internal organs.
    Therefore, with diseases of the intestines and stomach, acne may appear. A balanced diet (less sugar, fast food, baked goods) is also important. Read also Vitamins for hair loss: 10 of the best Review of the best vitamins for hair.

DRUGS USED FOR TREATING ACNE (Part 1)

Preferanskaya Nina Germanovna Associate Professor, Department of Pharmacology, Faculty of Pharmacy, First Moscow State Medical University named after. THEM. Sechenova, Ph.D.

This disease can occur at almost any age, from early childhood to old age, but most often occurs during rapid puberty in adolescents and in girls in the last week of the menstrual cycle. In almost 90% of cases, juvenile acne occurs, observed in patients 12–18 years old. However, over the past decades, cases of acne have become more frequent (up to 11%), which occur at older ages.

One of the most common causes of acne during adolescence is hormonal changes in the body. The active release of steroid hormones, especially androgens (male sex hormones), in both girls and boys, causes increased secretion of the sebaceous glands. Sebum changes its properties, turning from liquid into a dense and viscous secretion. There is hypersecretion of sebum, blockage of pores, papulopustular acne, nodular and cystic formations occur. The dense secretion of the sebaceous glands forms plugs in the ducts, clogs them and forms microcomedones. In the future, comedones are formed; they can be open (blackheads - blackheads) or closed (whiteheads - whiteheads). Comedones are localized on the skin of the face, chest, back, and later on the back of the neck. Open comedones look like black dots that clog the mouths of the hair follicles; when they are squeezed out, a white or brownish plug is released, consisting of thick sebum and horny scales. The black color of comedones is caused by melanin and not by pollution or oxidized sebum.

Closed comedones are small, slightly raised hemispherical papules of white color, and have a very small follicular opening. Closed comedones are the main potential source of inflammatory acne, when, along with sebaceous plugs, the superficial stratum corneum of the hair follicles thickens, and the compacted horny scales create an additional obstacle to the outflow of sebaceous gland secretions. Thickening of the superficial stratum corneum of the skin (hyperkeratosis) can develop under the influence of changes in hormonal levels, vitamin A deficiency, exposure to harmful chemicals or mechanical factors (friction, pressure) on the skin. All this creates a favorable environment for the development of the microbial process. The population of propionic bacteria, anaerobic pleomorphic diphtheroids (Propionibacterium acnes, Propionibacterium granulosum and Propionibacterium avidum) is growing, the staphylococcal flora (Staphylococcus epidermidis) and the yeast-like lipophilic fungus (Malassezia furfur) are activated.

If acne persists into adulthood, then this is a serious signal to think about your health. The appearance of acne can directly depend on the nature of nutrition and the state of the gastrointestinal tract. Very often, exacerbation of acne is associated with exogenous causes, such as masking acne with cosmetics, improper hygiene, a humid hot climate, the bad habit of touching areas of rashes unnecessarily, or even worse, squeezing out pimples.

There are mild, moderate and severe degrees of acne. For mild forms of acne, products for external use are mainly used. Treatment of moderate and severe forms should be comprehensive - local and systemic means.

PRODUCTS FOR EXTERNAL USE

First-line drugs in the treatment of acne - Benzoyl peroxide , Azelaic acid and Tretinoin - are effective with long-term use (3 months or more). Sometimes their use causes skin irritation, which is usually eliminated by reducing the frequency of application to the skin or reducing the concentration. The simultaneous use of 2 or more products is unacceptable; temperature changes and active insolation are harmful (Latin insolatio/insolare - “expose to the sun”).

√ Benzoyl peroxide has been used in dermatology for more than 20 years, has a pronounced antibacterial effect, promotes the dissolution of keratinized tissue, which allows it to be used for the treatment of mild to moderate acne. Treatment begins with a low concentration of the drug for 2–3 weeks, the concentration is gradually increased and used until the skin manifestations completely disappear. If local irritation is observed during treatment, the intervals between applications should be increased. The combination of benzoyl peroxide with antibiotics, azole compounds and sulfur preparations in combination preparations significantly increases their effectiveness. The drug is available in the form of a gel for external use under TN: “ Baziron AS ” (2.5 and 5% tube 40 g), “ Eclaran” (5 and 10% tube 45 g).

√ Azelaic acid has a pronounced antibacterial and anti-inflammatory effect. Prevents the formation of comedones and promotes their removal, while exhibiting an anti-comedogenic effect. Has a depigmenting and anti-acne effect. When using preparations containing azelaic acid, the production of fatty acids is reduced, oiliness is reduced and skin pores are cleansed. The drug under the TN " Skinoren" is available in the form of a 20% cream (tube, 30 g) and 15% gel (tube, 5, 15, 30 and 50 g).

Other preparations containing azelaic acid are “ Azelik” gel 15% (tube 30 g), “ Azik-Derm” cream 20% (tube 30 g).

√ Tretinoin is a synthetic retinoid, an analogue of vitamin A, produced under the technical names “ Isotretinoin” and “ Retin-A” (Retin ointment, 0.05 and 0.1% 10 g), “ Airol Roche” cream 0.05%, used for treatment of acne externally in case of ineffectiveness or individual intolerance to benzoyl peroxide. Eliminates existing comedones and prevents the appearance of new ones by normalizing the processes of keratinization of the epithelium and reducing the secretion of sebum.

√ Isotretionin + Erythromycin (TN " Isotrexin" , 10 g tube) - a combined retinoid gel with a macrolide antibiotic - has an antiseborrheic, anti-inflammatory and keratolytic effect, stimulates the growth of epithelial cells and affects their differentiation. Inhibits the terminal differentiation of sebocytes and hyperproliferation of the epithelium of the excretory ducts of the sebaceous glands, normalizes the composition and facilitates the removal of secretions, reduces the production of sebum and reduces the inflammatory reaction around the sebaceous glands. It affects comedonogenesis, inhibits follicular keratinization, and prevents the occurrence of acne caused by Propionibacterium acne. Erythromycin has a bacteriostatic effect against Propionibacterium acne. When used, side effects may occur in the form of burning, irritation, peeling of the skin, hyperemia, photosensitivity (increased sensitivity when in contact with sunlight).

√ “ Curiozin” (gel 10 and 5 g) contains zinc hyaluronate 15.4 mg, is used to treat acne of varying severity, promotes tissue restoration, improves cellular nutrition processes, and has antimicrobial activity. Hyaluronic acid is directly involved in the process of maintaining skin elasticity and turgor, has a stimulating effect on cell proliferation and restoration, has a beneficial effect on local microcirculation, and takes part in the process of natural wound healing. Zinc provides an antiseptic effect and accelerates wound healing. It is eliminated quite quickly after use, so the burning sensation and feeling of skin tightness that occurs at the beginning of treatment usually go away on their own.

ANTIBIOTICS FOR EXTERNAL USE

Treatment of acne with topical antibiotics is much safer than systemic antibiotics. Antibiotic therapeutic efficacy when used topically is significantly inferior to drugs containing benzoyl peroxide or azelaic acid, so the use of external antibiotics is justified only in case of intolerance to first-line drugs. The external use of antibiotics for acne is used to treat complicated forms of the disease. The disadvantages of antibiotic treatment include the development of an addictive effect and resistance of propionic bacteria.

√ Erythromycin ointment 1% (10, 15 g). The high antibacterial and anti-inflammatory activity of erythromycin is even more pronounced in its combination with zinc, produced under the trademark “ Zinerit” . Zinc, in turn, reduces the secretion of the sebaceous glands and loosens the pores, facilitating the local action of erythromycin.

√ Clindamycin (Dalacin) is a bacteriostatic antibiotic from the lincosamide group, which has a wide spectrum of action, is not addictive to skin microflora and is highly active against propionic bacteria and staphylococci. TN " Klindovit" gel 1% (30 g tube) - the drug is active against all strains of Propionibacterium acnes; after application to the skin, the amount of free fatty acids on its surface decreases from approximately 14 to 2%. The drug quickly accumulates in comedones, exhibiting antibacterial activity. The gel is applied in a thin layer to the previously cleaned and dried affected area of ​​the skin 2-3 times a day. To obtain a therapeutic effect, treatment should be continued for 6–8 weeks, and if necessary, can be continued for up to 6 months. An alcohol solution for external use containing 1% clindamycin per 100 ml is produced under the trademark " Zerkalin" . Excipients are ethanol, purified water and propylene glycol. The solution is applied to the affected area of ​​previously cleansed and dried skin 2 times a day, morning and evening. Klenzit S is a combined gel containing Clindamycin + Adapalene. Adapalene, a retinoid metabolite with an anti-inflammatory effect, normalizes the processes of keratinization and epidermal differentiation. Reduces the binding of follicular epithelial cells involved in the formation of microcomedones. Suppresses chemotaxis and chemokinetic reactions of human polynuclear cells. The gel is applied externally once a day (before bedtime) to previously cleansed and dried affected areas of the skin. The course of treatment is 2–4 weeks. If necessary, repeat the course of treatment. At the beginning of treatment, acne may worsen. If skin irritation occurs, the drug should be temporarily stopped or discontinued. It is necessary to avoid exposure to the sun and the use of artificial UV radiation (solarium).

√ Tetracycline (3% ointment). Tetracycline is a broad-spectrum antibiotic. It is used externally in the treatment of purulent skin infections (acne), prescribed for children over 11 years of age and adults. The drug is applied directly to the affected area of ​​the skin in a thin layer 1-2 times a day. With prolonged use of the drug, redness, discoloration of the skin, itching, slight burning at the site of application of the ointment, and photosensitivity may occur.

√ Levomycetin-Acri is available as an animent and solution for external use, used for bacterial skin infections caused by sensitive microorganisms. It has a bacteriostatic effect with a wide spectrum of action, disrupts the process of protein synthesis in the microbial cell. It is applied topically in the form of alcohol solutions and 5–10% liniment; the drug is applied to the affected surface several times a day.

√ Fusidic acid (fusidic acid) is used for skin and soft tissue infections caused by susceptible microorganisms. A cream is produced for external use under the Fusiderm . For external use, fusidic acid is applied in a thin layer to the affected areas of the skin 2-3 times a day for 7 days. In the area of ​​the affected areas, the drug penetrates deeply into the skin. When treating acne vulgaris, long courses of therapy are required.

√ Antiseptics are often used for acne on the chest and back. A mixture of salicylic alcohol 40 ml with the addition of 3 tablets of chloramphenicol (chloramphenicol) is moistened with a cotton swab and the rash areas are wiped morning and evening for 2-3 weeks. A mixture of salicylic alcohol + boric alcohol + chloramphenicol is also used. Based on salicylic acid, a whole series of very effective anti-acne lotions that do not contain ethanol are produced for problem skin. Lotions can quickly relieve inflammation, heal and eliminate acne of any complexity from the skin, and also stimulate the rapid healing of damaged skin areas. Benzoic acid has an antimicrobial effect, which inhibits the activity of enzymes in microbial cells and prevents the growth of bacteria. In medicine, it is used for skin diseases as an external antiseptic.

√ Dr. Theiss's acne cream - a combined drug - has a dermatoprotective, bactericidal, antibacterial effect; when used, the drug cleanses the skin and eliminates acne. The main active ingredient is triclosan, a chlorine-containing phenol derivative, which has an antiseptic effect. Triclosan is active against gram-positive and most gram-negative bacteria. Ethyl alcohol, sulfur in biosulfur, sodium tetraborate have an antiseptic and disinfectant effect, sulfur has antiparasitic and dermatoprotective properties. Glycerin gives the skin elasticity and protects it from drying out. The drug frees the excretory ducts of the sebaceous glands from horny masses, sebum, dust and causes a nonspecific anti-inflammatory effect.

How to choose an acne cream

When treating acne and pimples, an integrated approach is required, so just cream or gel is not enough. To choose the “right” remedy, you need to determine the cause of the rash. By the way, it often happens that one specific cream does not solve the problem, so you need to try several products. For acne, pharmaceutical creams or gels are usually prescribed, which contain anti-inflammatory components:

  • acids (azelaic, salicylic, kojic). They relieve inflammation, cleanse pores, and make skin tone more even.
  • essential oils with anti-inflammatory and calming effects (green tea, tea tree, aloe vera, eucalyptus, calendula).
  • absorbent minerals that absorb secretions from the sebaceous glands, as well as natural antibiotics (zinc, camphor, sulfur).
  • hyaluronic acid (for deep skin hydration).
  • retinoids, demethyl sulfoxide - for healing damage, regulating the functioning of the sebaceous glands.
  • cosmetic oils that help regenerate the skin (grape seed, olive, peach).

As for acne creams with antibiotics and hormones, they act faster, but they should be prescribed exclusively by a dermatologist. Treating the skin with such drugs is only allowed for a short period of time. If you use hormonal or antibacterial agents uncontrollably, unwanted side effects such as withdrawal syndrome or skin atrophy may develop.


Causes of acne

Photos from open sources

Hormonal disorders or what to do with acne in a teenager

A common cause of acne in teenagers is hormonal changes in the body. For example, girls experience more acne before and during menstruation. Although hormonal changes are considered normal in adolescence, if the rashes are severe and related problems, it is necessary to consult an endocrinologist and dermatologist. The dermatological clinic “PsorMak” offers comprehensive consultation and examination. We have the best specialists who will help you cope with acne.

Zenerite

One of the most popular remedies for acne and acne, which contains an antibiotic (erythromycin) and zinc salts. Erythromycin prevents the growth of bacteria, and zinc salts work as an antiseptic. If you have been prescribed "Zinerit" for acne, remember that it is not advisable to use it often and for a long time, because addiction develops and the drug simply stops working.

Zenerite
Astellas Pharma Europe, Russia

Zenerite powder for solution preparation (external use), 30 milliliter bottle - a medicinal product for the treatment of acne.
Resistant to cosmetic products. from 533

5.0 1 review

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Therapy

The most effective remedies for acne for teenagers are medications. Their appointment requires medical qualifications. The course of treatment should also be carried out under the supervision of a dermatologist. Medicines are produced in the form of tonics, creams, ointments. The choice of drug depends on the type of rash, the intensity of skin damage, the type of epidermis and the patient's medical history.

If you want to get rid of the problem once and for all, contact the PsorMak clinic. Remember that improper treatment of acne and the advanced course of the disease lead to its exacerbation and scarring on the skin. The so-called post-acne remains for life and is a serious cosmetic defect that has to be dealt with separately.

Don't experiment with your face!
Trust yourself in the hands of professionals and follow the recommendations of the specialists of the PsorMak clinic. June 14, 2020
Author of the article: dermatologist Mak Vladimir Fedorovich

Delex-Acne

This gel works well if you have mild to moderate skin breakouts. "Delex-Acne" is also prescribed for demodex (skin mites). An excellent product for home daily facial skin care, it is also used for the active treatment of acne as part of complex therapy. Delex-Acne contains sulfur, calendula and nettle. The acne gel does not contain hormones, antibiotics or alcohol, and therefore has no age restrictions for use. If you choose this gel, then it is optimal to combine it with lotion from the same series. You should use Delex-Acne gel no more than several times a week so as not to dry out the skin. The disadvantages of the product are that the smell is not very pleasant and that you can’t buy Delex-Acne in every pharmacy.

Delex-Acne
, Russia

The gel is characterized by anti-inflammatory, absorbable, antibacterial and sebostatic (drying) effects.
The drug in gel form is considered optimal for use in case of oily seborrheic skin, since the use of creams and ointments can increase the proliferation of harmful microorganisms. from 150

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Baziron

Acne gel "Baziron" exfoliates dead skin cells, which often “clog” pores, which is why pimples and blackheads form. The drug contains benzene peroxide and green tea, which dry out inflamed skin, normalize its cellular respiration and reduce secretions from the sebaceous glands. "Baziron" helps well with blackheads and subcutaneous pimples. The product perfectly moisturizes the skin.

Baziron AS
Galderma, Switzerland

Baziron AS is an allergy-resistant drug; the composition of this drug has been thoroughly tested for allergens, which ensured that the risk of an allergic reaction when using it is minimized.
The product has been dermatologically tested to identify any side effects that may irritate the skin, suitable for dry and sensitive skin. Does not contain alcohol. It also has anti-comedogenic properties, that is, it opens the fullicles and removes comedones (blackheads) on the nose. from 426

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Klenzit-S from Glenmark

This acne gel contains the antibiotic clindamycin, which fights acne by reducing inflammation. And adapalene (a derivative of vitamin A) moisturizes and regenerates the skin. If you find a pimple on your face in the evening and smear it with Glenmark Clenzit-S gel, the pimple will be gone in the morning. You can use the product for no longer than three months (once a day), because addiction may develop. Improvement in skin condition occurs after a week of using Klenzit-S. During treatment, peeling, burning and redness of the skin are possible. But after three weeks the skin gets used to it. It is better to wash your face with gentle, soft products at this time. During pregnancy and frequent exposure to the sun, you cannot be treated with Klenzit-S gel.

Klenzit-S
Glenmark Pharmaceuticals, India

A preparation for external use for the treatment of acne.
Before use, you should consult your doctor. from 486

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Where to start caring for a cosmetologist?

With skin cleansing (superficial and deep) depending on skin type, which is determined after examination through a magnifying glass.
Cleaning is carried out in several stages: cleansing with foam, disinfection with antiseptics, skin peeling, mechanical cleaning, applying a mask. The frequency of procedures is strictly individual and depends on the severity of the condition, skin type, season, effect of therapy and other factors. Typically, the course of treatment with timing and procedures is discussed at an appointment with a doctor. On average, facial cleansing is carried out once every 2-3-4 months. If this is a course of chemical peelings, then the procedure is usually carried out (also depending on the type of peeling) once every 2 weeks. A total of 3-5 procedures are required.

Perhaps a visit to a cosmetologist will not be enough; to combat acne you will have to involve other specialists: a dermatologist, gynecologist, gastroenterologist, endocrinologist. Acne treatment should ideally begin with a diagnosis of the body. You will need to take a general blood test, a stool test for dysbacteriosis, microscopy of skin scrapings and a number of other studies.

Published on the portal parents.ru

Differin

The active ingredient in this gel for acne and pimples is adapalene (retinoid). Differin is indicated for people with combination and oily skin. Judging by patient reviews, this drug really works, although it is inexpensive. An important advantage of this gel is that it removes acne and scars on the skin. You can use Differin for a long time because it does not contain an antibiotic.

Differin
Laboratoires Expanscience, France

A drug for the treatment of acne, for external use.
from 624

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Proper nutrition

Skin largely reflects our lifestyle. When you abuse fried and fatty foods, toxins enter the bloodstream and negatively affect the condition of tissues. Doctors recommend sticking to a healthy diet, consuming enough proteins, complex carbohydrates and fiber. The latter ensures normal functioning of the gastrointestinal tract and prevents the formation of constipation, which also has a positive effect on skin health.

If possible, you should avoid smoked meats, mayonnaise, chocolate, and processed foods. Both the abundance of flour products and excessive consumption of sugar have a negative impact on the appearance. Often, restrictions on sweets give quick and visible results.

Juniper from Mi&Ko

Acne cream perfectly fights acne and other imperfections of problem skin. “Juniper” can be applied not only to the face, but also to other areas of the body where there are rashes. Use the cream morning and evening. The drug relieves inflammation and destroys bacteria, nourishes the skin, moisturizes, and reduces sebum production. Juniper cream is suitable for both teenagers and those who have pimples and acne due to hormonal imbalances or with age. According to customer reviews, the cream smells nice, has a comfortable texture, is not tested on animals and is inexpensive.


Types of skin rashes

Photos from open sources

Juniper from Mi&Ko cream
MiKo, Russia

Face cream Juniper consists of 24% organic raw materials. The new formula contains lavender hydrolate and boswellia extract, which instantly improve complexion, eliminate dryness and inflammation, and protect the skin from stress. A unique extract of wintergreen leaves eliminates rashes and stimulates skin renewal. With Juniper cream, your skin will be healthy and smooth, which will be the key to self-confidence!
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What to avoid

When considering the question of how to treat acne in a teenager, you should dwell on the causes of exacerbation. New rashes can be caused by the following factors:

  • abuse of fatty and sweet foods;
  • water shortage;
  • lack of hygiene;
  • infection of acne with dirty hands;
  • self-squeezing pimples and injuring nearby skin areas.

Often, inflammatory processes are provoked by bacteria that enter clogged ducts. To avoid this, experts recommend:

  • make sure that the hair does not cover the skin of the face;
  • do not touch the inflammation with your hands;
  • do not scratch the rash;
  • Do not squeeze pimples yourself.

Neglecting the rules will make the problem worse.

Clearasil Ultra

Clearasil cream is sold in almost any store or pharmacy. Contains salicylic acid, cocoglycosin, allantoin, aloe extract, glycerin, lavender extract, Italian immortelle extract, cistus Montpelient extract. The product relieves inflammation well, is applied precisely and quickly solves the problem of acne and acne. The instructions say that the Klerasil cream will remove a pimple in 4 hours! The drug has a slight mattifying effect. And although the tube of cream is small and not cheap, Klerasil is used very sparingly, so it will last for a long time.

Clearasil Ultra
Reckitt Benckiser, Netherlands

Active components relieve inflammation, redness and irritation, normalize the structure of the epidermis, and promote exfoliation of dead cells.
Thanks to AcceladermTM technology, the cream enhances the effect, allowing the active ingredients to penetrate deeply into all layers of the skin. from 205

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Lumene Nordic Girl! Clear It Up!

This acne cream tightens pores, removes oily shine and is great for spot application. Featuring Lumene Nordic Girl! Clear It Up! There are no dyes, parabens or mineral oils, so the product is suitable even for sensitive skin. The cream contains salicylic acid, arctic plantain extract and vitamin B3. The product relieves pain from subcutaneous inflammation, cools, evens out skin texture, and removes acne scars. The cream is absorbed well and does not leave a film, so it can be applied both under and on foundation.

Lumene Nordic Girl! Clear It Up!
Farmia, Finland

Cream for oily and combination skin Lumene Nordic Girl!
Clear It Up! Oil Free Moisturizer helps control shine while effectively hydrating skin and tightening pores. Helps deal with acne. With regular use, it helps reduce the appearance of blemishes. Consists of 100% plant ingredients. from 535

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Skinoren

This cream contains azelaic acid, which helps regulate sebum secretion, fights pathogenic bacteria, and relieves inflammation. “Skinoren” has proven itself well even in advanced stages of acne, although long-term treatment with this remedy is undesirable. Skinoren dries out the skin, so it is better not to use it if you have peeling. Apply the cream morning and evening to the affected areas of the skin and rub in lightly.

Skinoren
Intendis Manufacturing, Italy

Skinoren is a drug for the treatment of acne vulgaris or juvenile acne and hyperpigmentation.
from 349

4.0 1 review

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Effaclar Duo + by La Roshe-Posay

Cream-gel is indicated for inflammation of the skin, for mattifying and deep moisturizing, prevention and treatment of acne. Effaclar Duo + contains thermal water (moisturizes the skin), prokerad (fights post-acne), lipo-hydroxy acid salicylic acid (renews epidermal cells, regulates sebum production, lightens spots on the skin). An excellent remedy for treating moderate acne. The instructions say that the positive effect occurs within 12 hours after the first use of the cream-gel. Effaclar Duo + is suitable not only for spot treatment of acne, but also for the entire face. The product has a good texture, is quickly absorbed, dries out rashes, does not leave a greasy sheen or stickiness, and does not tighten pores. Can be used as a base for makeup.

Effaclar Duo+
La Roche-Posay, France

Effaclar DUO(+) against the re-formation of imperfections. Light cream-gel EFFACLAR DUO(+) moisturizes the skin for 24 hours and provides a long-lasting mattifying effect. By adding two new active ingredients - Aqua Posae Filiformis and Mannose - the product restores the skin microbiome, which helps reduce the incidence of inflammation. Efaklar DUO(+) contains Prokerad, which prevents the appearance of residual marks from imperfections (post-acne) in the form of red and dark spots. Is an excellent base for makeup.
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