The Bio-expander drug differs from others in that it contains both bound hyaluronic acid filler and free hyaluronic acid. In ultra-modern, space-like laboratories of the Regenyal Laboratories concern, from the purest hyaluronic acid without protein impurities, using long-term mixing at low temperatures using MUCH technology, free hyaluronic acid is “embedded” into stabilized, filler. The output is hyaluronic acid containing a very small amount of the stabilizing agent BDDE, and free hyaluronic acid bound to it by hydrogen bonds. Regenyal Laboratories scientists conduct many studies on the effect of hyaluronic acid ester not only on skin cells, but also on CD44 receptors adipocytes and preadipocytes, that is, adipose tissue cells, and receive confirmation of its stimulating effect on adipose tissue.
What are the benefits of Bio-expander?
The fact is that it is based on low-viscosity, high-molecular hyaluronic acid of two molecular weights: 1 million Da and 2 million Da. When mixed with the stabilizing agent BDDE for a long time, much less of it is required, and, accordingly, less bonds. The drug also contains 10% low molecular weight hyaluronic acid with a molecular weight of 500,000 Da. This product breaks down gradually, slowly and for quite a long time, up to six months, in different areas of the fatty tissue, all the time releasing low molecular weight molecules of hyaluronic acid, which have a long-term moisturizing and toning effect on the skin in the area of the drug injected into the subcutaneous fatty tissue. In addition, along with moisturizing the skin, it whitens and reduces pigmentation, as after a long course of biorevitalization, but here, mind you, only after one (!) procedure. In addition, Bio-expander is very flexible and is distributed even in very thin subcutaneous tissue without any contouring or visualization. To facilitate its insertion and complete painlessness for the patient and the absence of traces of the procedure, 27G cannulas are included, which allow precise sliding even in a very thin layer of subcutaneous tissue. You can also use small short needles 30G 4 mm for injections.
Bio-expander is used on the face and throughout the body, where the skin becomes like a slightly dried out apple when the smooth and tight “substrate” in the form of subcutaneous tissue disappears. This includes the forehead with its wrinkles, cheeks, perioral purse-string wrinkles, neck, décolleté, hands, skin above the knees, elbows, on the stomach... All areas of the face and body where it is necessary to restore the layer of subcutaneous tissue, moisturize and rejuvenate the skin.
Biorevolumetry - a new concept
The new products, developed by specialists from Fidia Farmaceutici and Regenyal Laboratories, are based on the highest quality hyaluronic acid, which does not contain impurities or preservatives. This class of drugs is called biorevolumetrics, and the new concept of rejuvenation is biorevolumetrics.
How do biorevolumetrics differ from the biorevitalizants we are familiar with? Biorevitalizants are injections whose main function was to improve the quality of the skin, moisturize it and stimulate cellular activity. In addition to this function, biorevolumetrics act as volumizers, that is, they not only improve the condition of the skin, but also allow you to add additional volume to the tissues. Thus, the biorevolumetry procedure is a physiological volumization with an immediate revitalizing property.
Aziza Usmanova comments:
Before the advent of biorevolumetrics, volumization of the face was carried out using fillers. To improve the condition of the skin, we additionally resorted to the help of biorevitalizants. With the advent of a new concept of environmentally friendly rejuvenation, we solve 2 problems at once in 1 procedure - we improve the volume relief and structurally rejuvenate the skin. A conceptually new approach to rejuvenation and new opportunities allowed us not just to camouflage imperfections, but to influence their nature in the most natural way.
Who is indicated for the biorevolumetry procedure using the Bio-expander drug?
The use of the drug is classified as a universal anti-aging agent. Bio-expander is indicated for use by patients of different ages (25–75 years), with different skin types and conditions. The result after the procedure is very pleasing both for thin, dry faces prone to the formation of many small wrinkles, and for normal skin thickness. It is used for the treatment and rejuvenation of the area of the temples, forehead, cheeks, around the mouth - these are the same “barcode” wrinkles, also called “purse-string” wrinkles, and moisturizing the lips.
About the new method of volumetric correction
Biorevolumetry is the newest correction method that can not only restore volume lost over time (through contouring), but also significantly rejuvenate the face (through biorevitalization).
To understand what biorevolumetry is, it is enough to divide this term into its components: “bio” - life, “re-” - repeat, “volumen” - volume, that is, restoration of lost volume.
There are two types of volume loss (hypovolumetry):
- Local, which is divided into acquired and constitutional, is characterized by a deep or superficial decrease in adipose tissue on the face.
- A change in the structure of the skin and its components, in which the amount of water is significantly reduced, is called hypovolumetric destructuring.
What effects can be achieved using this product?
You can even out and rejuvenate the skin texture, smooth out wrinkles, strengthen weakened tissues, they become more elastic, their resistance and the quality of skin structures increase, eliminate the beginning sagging of the contours of the face and body (neck, décolleté, hands, inner surface of the shoulder, elbows, knees) . Get deep tissue hydration and structural rejuvenation. How does this manifest itself? Pinch your skin into a crease on your cheek or smile broadly. Are the fine wrinkles that appear on the skin of the cheek visible? So, the use of Bio-expander allows you to remove them or significantly reduce them. Along with a significant improvement in skin smoothness and color.
Eco-friendly "green" injections
The company Fidia Farmaceutici SpA (Italy) and Regenyal Laboratories (Italy) have developed a completely new class of injectable drugs - biorevolumetrics. Procedures using these materials have come to be called “green”, since they fully meet environmental standards.
Not only the biorevolumetrics themselves are environmentally friendly, but also the entire process of their production, based on energy-saving technologies - a professional water purification system, materials from clean renewable sources, highly purified hyluronic acid without impurities is used as raw material. Thus, the final product of this production is completely safe. Along with safety, technologists have prioritized the quality and effectiveness of procedures performed using biorevolumetrics.
Eco-friendly production of biorevolumetrics
Aziza Usmanova comments:
“Green” injections are an opportunity to perform youthful procedures without fear that in the distant future the drugs used will become a risk factor for the patient. Eco-friendly non-surgical rejuvenation guarantees that the tissues will continue to live according to physiological canons after the procedure.
3 key components of the term “biorevolumetry”: “bio” - drugs consist of biocompatible active substances; “re” - regeneration function and structural restructuring; “volumetry” - reconstruction of volume.
Healing period
The drug has a high degree of safety; no papules or hematomas remain. Painful sensations, swelling and redness last no more than a week. After complete healing, the effect lasts from 9 to 12 months.
The patient must follow the rules of care for a quick recovery and prevention of undesirable consequences:
- during the first days you cannot use decorative cosmetics;
- after cleansing with soft foams from the professional line, the injection areas are treated with Bepanten or Curiosin;
- you need to limit the consumption of salt, strong tea and coffee, alcoholic beverages are prohibited;
- You need to protect your face from sunlight for about a month and apply cream with SPF factor;
- You cannot visit the sauna, solarium, swimming pool, beach, play sports, perform hardware procedures, massage.
How is the procedure performed in clinics?
During the consultation, the cosmetologist assesses the condition of the skin and tells the patient what problems can be solved with injections.
The survey reveals the presence of chronic diseases and allergic reactions. Before carrying out invasive rejuvenation, a number of recommendations should be followed:
- You should not take antibiotics or other medications that affect clotting processes for about a month;
- During the week you should not visit the sauna, solarium, beach, do deep peeling or mechanical cleaning;
- reduce salt intake, prohibit alcoholic drinks;
- Smoking on the day of the procedure leads to a long recovery period.
How to minimize the effect
Hyaluronic fillers are highly safe and have no side effects. But in some cases, negative consequences are still observed.
If symptoms persist for more than 10 days, your doctor may prescribe antihistamines. Lymphatic drainage massage and microcurrents will help speed up elimination.
Correction methods and number of sessions are selected individually.
Attention! A hyaluronidase solution has a quick effect, but due to the risk of swelling, cosmetologists use it in extreme cases.
Advantages and disadvantages
It is important for patients to know the undeniable advantages of Italian fillers, as well as take into account the disadvantages of injection rejuvenation.
Pros:
- versatility of use allows you to cope with a number of aesthetic defects;
- creating a natural correction without disrupting facial activity;
- target areas - face, neck, décolleté;
- compatibility with any skin type;
- painlessness;
- the result lasts up to 12 months;
- Appointed from 30 to 75 years of age.
Flaws:
- high price;
- performed by a doctor on an outpatient basis.
Contraindications and consequences
Contraindications to biorevolumetry are common to all types of cosmetic procedures. These include:
- period of pregnancy and lactation;
- blood diseases;
- inflammatory changes in the area of proposed injections;
- hypersensitivity to the components of the drug, including hyaluronic acid;
- severe heart disease;
- renal and liver failure;
- infectious disease;
- exacerbation of chronic pathologies.
As with any injection method of administering the drug, complications are possible after the procedure (redness in the injection area, swelling of the soft tissues of the face, infection, etc.).
Manufacturer of a line of biorevitalizants
2 Italian companies are engaged in the production of biogel. Regenyal laboretories specializes in the research and creation of pharmaceutical and cosmetic products based on hyaluronic acid. An innovative cross-linking technique has been patented, in which the percentage of BDDE agent tends to zero. A high degree of purification prevents side effects.
Attention! The raw material base is produced in Fidia Farmaceutical laboratories, as a result the final product does not have protein residues or impurities.
Comparison with other popular fillers
Regenial Idea - hyaluronic gels for volumetric procedures. The composition contains stabilized and unstabilized acid of non-animal origin. Prescribed for lip augmentation, contouring, creating a relief oval, rejuvenating the skin of the face, neck, and décolleté. The visible results last for about a year.
Aquashine - the filler is based on vitamins, peptides, coenzymes, amino acids, and hyaluron. Used to improve the condition of the dermis, combat age-related processes, pigmentation, and moisturize the skin. Requires a course and is used for patients of different age groups.
Juvederm Hydrate - contains unstabilized hyaluron and the antioxidant mannitol. After 3 procedures, hydration, tissue tightening, reduction in the number and depth of wrinkles, and improved elasticity are observed. The effect lasts from 6 to 12 months.
Mezovarton - hyaluronic cocktails also contain amino acids and vitamins. Prescribed for patients over 40 years of age, the use allows you to increase the number of stem cells. The prolonged result lasts up to a year.
Patient reviews
The use of regenyal idea is discussed on forums, with mostly positive reviews.
The user writes about good results, lightening of color, smoothing out wrinkles.
The participant describes the experience of use, the absence of swelling, smoothing of nasolabial folds, and a rested appearance of the face.
The user writes about the features of the staging technique.
The user describes the experience of a friend, the short duration of the effect.
The review describes negative consequences, periodic inflammation, swelling, and pain.
Types of drugs
Regenyal Idea - used to correct medium and deep folds. Also prescribed for contouring when there is a lack of volume in the zygomatic area. It is characterized by high elasticity and compatibility with fabrics. Degradation of hyaluron occurs within 9 months. Available in the form of 0.6 and 1 ml syringes.
Bio expander - prescribed for biorevolumetry, reducing the number of wrinkles, restoring the oval. Creating stiffeners and local volume allows you to stop the displacement of the contour. Effectively copes with deep creases in the nasolabial triangle, bridge of the nose, and forehead folds. Course therapy is prescribed starting at age 30. Unlike similar drugs, a visible rejuvenation effect is observed even after 50, the results are comparable to plastic surgery. Used to rejuvenate the neck area, in particular, eliminates Venus wrinkles. The result is observed for about a year. The package contains 3 syringes with a volume of 1.1 ml.
Lips is a low-viscosity monophasic gel designed to correct the shape of the lips, add volume, and eliminate wrinkles in the perioral area. In addition to the pronounced aesthetic effect, it is possible to improve the condition of thin, delicate skin, restore moisture balance, and cope with dryness and flaking. The effect lasts up to 12 months. Available in the form of a 1 ml syringe.
Instructions for administering the drug
According to the protocol, standard skin preparation is carried out: cleansing, antiseptic treatment, application of anesthetic ointment. You can trust implantation only to a specialist with a higher medical education.
Instructions:
- storage at room temperature in original packaging;
- implantation is performed by a doctor on an outpatient basis;
- the package is opened in front of the patient;
- target areas of the cosmetic procedure - forehead, temples, cheekbones, cheeks, nasolabial, perioral, corners of the mouth, chin, hands, décolleté, neck;
- the depth of injection depends on the objectives of the procedure; it is implanted into the middle and deep layers of the dermis;
- needle components are used; after implantation, the syringe is also disposed of; storage and subsequent puncturing is prohibited.
Administration schemes:
- Pyramidal - is prescribed for sculpting the cheekbones and correcting severe ptosis. The injection pattern resembles a pyramid; 27G needles with a length of 19 mm are used for injection. The base is located in the orbital area, and the apex, the supposed pyramid, reaches the level of the upper lip. Implantation is carried out into the deep layers of the dermis using a linear-retrograde technique. The maximum volumes of the drug are administered in the zygomatic region; as you move down, the dosage decreases. The distance between the lines is about 5 mm.
- Vertical - used to correct the periorbital area, with pronounced purse-string wrinkles, to lift the corners of the lips. Implanted with needles measuring 27–30G, 4 and 13 mm long. The introduction is carried out at a right angle, the depth is determined with less resistance, which is due to the presence of voids in the subcutaneous layer. The intervals between injections are from 3 to 4 mm, the dosage is determined individually.
- Lip liner - prescribed for women under 35 years of age with clear lip edging, absence of wrinkles in the perioral area, to increase volume, and correct asymmetry. Injections are carried out along an imaginary line parallel to the red border, at a distance of 4 mm from the border. Needles of size 27G, length 19 mm are used, and are inserted into the mucous membrane along its entire length. At the exit of the needle, the biogel is slowly introduced; 2 punctures in one direction are enough. Visually, the lips turn out, which gives them pronounced volume.
Where and for how much can I buy
Biofillers are sold in specialized online stores. When purchasing, you need to check the batch number, certification, and expiration date. Only if you have a complete package of documents can you protect yourself from purchasing counterfeit products.
The official distributor is the company Fitogen. It is not recommended to purchase from private individuals, and also at a significant discount; they often offer a fake in this way.
Expert advice. Patients should not purchase hyaluronic fillers on their own. If the rules of storage and transportation are violated, the effect of the procedure is difficult to predict.
The cost of the lip gel is 4,300 rubles, the reginal idea is 6,000 rubles, the reginal bio expander costs 7,000 rubles.
Opinion of cosmetologists
Cosmetologists on forums discuss the features of volumetric products.
The user writes that he uses a bio expander to fill neck wrinkles.
The participant does not recommend using 2 ml for lip augmentation; 1 ml is enough.
The review describes the softness, plasticity of the drug, and the absence of side effects.
Precautionary measures
Invasive procedures require compliance with a protocol performed on an outpatient basis by a cosmetologist with a higher medical education. During the consultation, it is important to identify possible contraindications:
- pregnancy, lactation;
- respiratory diseases;
- autoimmune pathologies;
- blood clotting disorder;
- herpes;
- postoperative period;
- oncology;
- individual intolerance;
- tendency to keloids.
Side effects usually disappear within 7 days:
- swelling;
- painful sensitivity;
- redness;
- hematomas;
- inflammation;
- asymmetry.
