Review of popular liquid prostheses for the treatment of arthrosis

With age, the synthesis of natural hyaluron in the body decreases, which leads to discomfort in the joints, pain, and limited mobility. Hyaluronic acid, produced in older people, has a low molecular weight, so its concentration in cartilage is not enough for its normal functioning.

To compensate for the deficiency of natural synovial fluid, traumatologists and orthopedists recommend intra-articular injections of liquid prostheses based on sodium hyaluronate, as well as their synthetic analogues. After each course, the motor activity of the joint improves, the structure of the cartilage and its internal structure are restored. The only “but” is that the effect is temporary, and its duration depends on the medication. What is the difference between the liquid dentures that are most commonly used today?

Not all liquid synovial fluid grafts are equally effective

What are the differences between drugs based on sodium hyaluronate and synthetic ones?

Means for restoring synovial fluid have appeared relatively recently, and hyaluronic acid, or sodium hyaluronate, its sodium salt, was chosen as the first active ingredient for replacement. It is a natural polysaccharide, a natural component of the connective tissues of the human body. There is especially a lot of hyaluronic acid in synovial fluid.

Sodium hyaluronate molecules have high hydrophilic properties - each of them attracts up to a thousand water molecules. Once inside the joint space, they restore the visco-elastic and shock-absorbing properties of the fluid.

Somewhat later, orthopedic traumatologists had access to synthetic polymer preparations, for example Noltrex, which in many respects surpassed those based on sodium hyaluronate. Noltrex is characterized by absolute biological compatibility with human tissues, therefore it does not cause allergic reactions or rejection.

The drug fills the joint space, enlarges it and normalizes the biomechanics of the joint by restoring synovial fluid. The interval for administering injections of the synthetic agent is increased due to its prolonged action - from 9 months to two years.

To treat arthrosis of the knee joint, one to four Noltrex injections per course is sufficient.

Types of injections for facelift

Injection rejuvenation is divided into seven categories:

  1. injections of drugs that block the function of certain facial muscles;
  2. injections of hyaluronic acid preparations;
  3. injections of collagen-containing preparations;
  4. introduction of meso-cocktails under the skin;
  5. autologous plasma rejuvenation procedure;
  6. volume replenishment with absorbable gels;
  7. introduction of mesothreads under the skin.

All methods of lifting the oval face have contraindications. If it is impossible to carry out injections, the doctor will recommend you a hardware or surgical method of lifting.

Many injections are performed using local anesthesia. After applying it, the doctor waits 15-20 minutes for the anesthesia to take effect. Procedures such as plasma lifting or collagen rejuvenation are usually done without anesthesia.

Review of some liquid prostheses based on sodium hyaluronate

1. Gialgan Phidias

One of the most affordable products with a very low molecular weight, which is an aqueous solution of hyaluronic acid. The fluid is quickly distributed in the joint capsule, but is also quickly absorbed into the ligaments and adjacent muscles. A local reaction is possible within 24 hours after administration.

Some liquid hyaluronic acid-based prostheses lead to swelling and redness of the skin

2. Duralan

A product with a low molecular weight is recommended for use during remission - to maintain joints. In large ones, a dosage of 3 ml is administered, in small ones - 1 ml, in courses with an interval of six months.

3. Fermatron

The drug is indicated for moderate forms of osteoarthritis and is available in sealed glass syringes with a volume of 2 ml. The medicine is not patented, so its pharmacokinetics have not been studied enough. There are virtually no clinical indications regarding interactions with other medications. The drug, however, is approved for use during pregnancy and lactation, although many doctors prohibit its administration during pregnancy, as well as in patients under 18 years of age.

The maximum period of action of Fermatron is up to 6 months

4. Adantom

Produced by a Japanese pharmaceutical company in syringes, it contains 25 milligrams of the active substance - sodium hyaluron. Before administration, the viscoelastic agent is warmed and injected using a 22G needle.

5. Sinokrom

A special feature of this medication is a specialized lock on the disposable syringe, which prevents accidental opening of the container. The product is administered in a course of six injections every one week. Manufacturer: Austrian pharmaceutical company.

6. Ostenil

This Swiss development is also based on hyaluronic acid. The drug must be stored in a cool, dry place, and before administration, make sure the syringe is tight. Hyaluronate and mannitol in the product protect joints from free radicals, which somewhat prolongs the duration of the medication. The course involves at least 3-5 injections. After each of them, a burning sensation is possible, which is eliminated with ice.

7. Hyastat

One of the Russian developments, produced in a sterile disposable syringe with a capacity of 20 milligrams. Before administration, the patient is always given an x-ray of the joint, and general clinical blood and urine tests are taken to exclude inflammatory processes in the body. If the outcome is positive, the course of treatment is repeated after a year.

Giastat is administered in courses of 3-5 injections at intervals of several months.

8. Go On

Another product based on sodium hyaluronate, which demonstrates stable positive dynamics in the treatment of arthrosis and osteoarthritis. Used to replenish synovial fluid deficiency.

9. Synvisc

Biological analogue of hyaluronic acid with high molecular weight – 6,000,000 Daltons. For the treatment of arthrosis of the knee joint, 3 injections are recommended at intervals of a week. For diseases of the hip, shoulder or ankle joint, one injection is performed, and to achieve a better effect, a second one is performed 1-3 months later. The effect, according to clinical indications, is on average up to 26 weeks, with a maximum of 52 weeks in the treatment of knee osteoarthritis.

Synvisc – a drug with maximum molecular weight – lasts from 6 to 12 months

Injection facial rejuvenation methods

Injection lifting procedures, according to the specifics of the action, can be divided into four groups:

  1. muscle blocking;
  2. rejuvenation with drugs;
  3. correction of volumes and shapes;
  4. creation of a skin frame.

The first group includes Botox and Dysport. This type of lift is described in more detail below. The second group includes mesotherapy, biorevitalization, collagen rejuvenation, plasma lifting. Using thin needles, the doctor injects various substances under the skin, the action of which is aimed at activating the functioning of cells. In mesotherapy, special cocktails are used - mixtures containing medications. Biorevitalization is the moisturizing and transformation of the skin using hyaluronic acid. Collagen injections are a popular method of improving skin quality, a hit of 2019. Plasmolifting is a non-surgical method of rejuvenation, which is based on the injection of enriched platelet plasma under the skin.

The third group includes fillers that differ in the duration of the effect. More details about contour plastic surgery are discussed below. Finally, the fourth category. In this case, the formation of a tightened skin frame is carried out by introducing mesothreads. Being biocompatible, they are not rejected by the body and dissolve over time. After administration, a collagen frame is formed around the threads, which remains after the drug is removed from the body.

Facial rejuvenation with Botox: advantages and disadvantages

Botox and its analogue Dysport are used to eliminate:

  • "crow's feet";
  • wrinkles in the corners of the mouth;
  • folds in the area between the eyebrows;
  • longitudinal wrinkles on the forehead.

Botulinum toxin immobilizes muscles that are involved in active facial expressions. Any wrinkle located in the injection area is smoothed out and becomes invisible. When the drug is administered correctly, relaxation of these muscles does not affect facial symmetry and overall appearance. You can do the same actions: smile, be surprised, frown. Emotions will be less expressed on the face, but still readable.

Pros of Botox injections:

  • injections are carried out with a thin needle, the procedure is comfortable;
  • no traces of injections remain;
  • the recovery period takes a couple of days;
  • existing wrinkles are smoothed out and “frozen,” as it were, and new ones do not appear at the injection sites throughout the entire duration of the drug.

After the session, you will forget about wrinkles for six months. The procedure is completely justified in terms of price and quality.

Disadvantages of the procedure:

  • sometimes after administration of the drug, small bruises are observed for a couple of days;
  • it is possible to develop inflammation at the injection site with improper care;
  • a doctor with insufficient experience can disrupt the symmetry of the patient’s face;
  • Abuse of Botox can create a “mask” effect.

To avoid side effects, trust the care of your beauty to experienced, certified professionals.

Differences in molecular weight

All liquid synovial fluid prostheses are divided into three groups based on molecular weight. Those in which it is as high as possible are considered more effective, since each of them has multiple intermolecular cross-links. Due to them, the medicine dissolves for a long time and during this entire time provides an analgesic, anti-inflammatory and wound-healing effect.

Molecular weight, DaltonMedicinesAverage cost per injection, rub.Clinical features
500 000 – 730 000Gialgan Fidia (Italy), Intragel (Italy), Suplasin3000-4500Large number of injections, minimal duration
1 000 000Ostenil, Fermatron plus (UK), Viscosil, DuralanFrom 4000-5000Requires approximately 5 injections per course, but the effect is short-term
2 000 000-3 000 000Synvisc (USA), Sinokrom form, Giastat (Russia), Gialux (South Korea), Visco plus (Germany)From 3000 to 20,000Number of injections – less than five, effect – several months
6 000 000-7 000 000Synvisc One (USA), Synvisc GilanFrom 23 000The effect is longer lasting
More than 10,000,000Noltrex3000The effect lasts for more than a year with a minimum number of injections per course

Lack of active movement in old age quickly worsens the symptoms of arthrosis. A simple experiment will show why this happens:

It is most promising today to treat arthrosis, regardless of its degree, with synthetic viscoprostheses. Due to their high molecular weight, such products, for example Noltrex, provide a long-lasting effect, and due to the polymer structure they have virtually no contraindications or side effects.

Rehabilitation after injections

It will take 3 to 14 days to fully recover from the injections. In most cases, visiting the solarium, swimming pool and sauna is prohibited. A ban on the use of decorative cosmetics is also common. Special local care is prescribed for the injection sites. In the first days, physical activity is excluded; you should not rub or scratch the injection sites.

Botox will not work if you drink alcohol after the session, so you will have to give up alcohol for 10-14 days. After two weeks you can judge the result. You come for an examination to a cosmetologist and, if additional correction is required, it is carried out on the same day.

Video

Injections for facial skin tightening: price in Moscow

Method Price
Botox/Dysport 380 / 95 rub. for 1 unit
Fillers from 10,000 rub.
Biorevitalization from 10,000 rub.
Mesotherapy from 4550 rub.
Collagen rejuvenation from 5000 rub.
Plasmolifting (method of R. Akhmerov) from 6,000 rub.
Plasmolifting RegenLab (Switzerland) from 15,500 rub.

The introduction of drugs under the skin can be combined with laser and hardware procedures, as well as plastic surgery. Many patients practice an integrated approach to preserving beauty, and we regularly reduce the cost of facial contour lifting methods as part of seasonal promotions. All so you can afford more!

In our clinic, all specialists are proficient in injection cosmetology methods. Each doctor is certified in injection lifting training. Your beauty is our profile.

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